. 2021 Feb 19;71(4):413–420. doi: 10.1016/j.bjane.2021.02.020

Table 1.

Description of the selected studies.

Year of publication of the study	Intervention	n	Age range (years)	Procedure
Kim 2013²⁴	DEX 0.4 mcg.kg⁻¹.h⁻¹	50	20–58	Nose surgery
Kim 2013²⁴	Saline	50	20–58	Nose surgery
Ham 2014²⁵	DEX 0.1 mcg.kg⁻¹	34	20–45	Orthognathic surgery
Ham 2014²⁵	Saline	36	20–45	Orthognathic surgery
Kim 2015¹⁵	DEX 0.4 mcg.kg⁻¹.h⁻¹	57	≥65	Orthopedic surgery
Kim 2015¹⁵	Saline	58	≥65	Orthopedic surgery
Yang 2015²⁶	DEX 0.5 mcg.kg⁻¹.h⁻¹ and 0.2–0.7 mcg.kg⁻¹.h⁻¹	39	18–80	Oral and maxillofacial surgery
Yang 2015²⁶	Saline	40	18–80	Oral and maxillofacial surgery
Ding 2015²⁷	DEX 0.8 mcg.kg⁻¹.h⁻¹	20	45–80	Cystectomy
Ding 2015²⁷	Saline	20	45–80	Cystectomy
Liu 2016¹⁶	DEX 0.2–0.4 mcg.kg⁻¹.h⁻¹	100	65–80	Orthopedic surgery
Liu 2016¹⁶	Saline	100	65–80	Orthopedic surgery
Li 2016²⁸	DEX 0.6 mcg.kg⁻¹.h⁻¹	30	18–65	Open gastrectomy
Li 2016²⁸	Saline	30	18–65	Open gastrectomy
Lee 2016²⁹	DEX 0.1 mcg.kg⁻¹.h⁻¹	50	≥20	Thoracoscopy
Lee 2016²⁹	Saline	50	≥20	Thoracoscopy
Kwon 2016¹⁴	DEX 0.5 mcg and 0.5 mcg.kg⁻¹.h⁻¹	30	30–80	Transurethral resection of the prostate
Kwon 2016¹⁴	Saline	30	30–80	Transurethral resection of the prostate
Moshiri 2016³⁰	DEX 0.5 mcg.kg⁻¹.h⁻¹	25	18–50	Electroconvulsive therapy
Moshiri 2016³⁰	Saline	25	18–50	Electroconvulsive therapy
Song 2016³¹	DEX 0.5 mcg.kg⁻¹.h⁻¹	25	18–60	Craniotomy
Song 2016³¹	Saline	27	18–60	Craniotomy
Deiner 2017³²	DEX 0.5 mcg.kg⁻¹.h⁻¹	189	≥68	Non-cardiac elective surgery
Deiner 2017³²	Saline	201	≥68	Non-cardiac elective surgery
Lee 2018³³	DEX 0.1 mcg.kg⁻¹ and 0.2–0.7 mcg.kg⁻¹.h⁻¹	95	≥65	Non-cardiac surgery
Lee 2018³³	Saline	109	≥65	Non-cardiac surgery
Tang 2018³⁴	DEX 0.1 mcg.kg⁻¹ and 0.3 mcg.kg⁻¹.h⁻¹	54	18–70	Neurosurgery
Tang 2018³⁴	Saline	52	18–70	Neurosurgery
Sun 2019³⁵	DEX 0.1 mcg.kg⁻¹.h⁻¹	281	≥65	Non-cardiac surgery
Sun 2019³⁵	Saline	276	≥65	Non-cardiac surgery

Total		2,183