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. 2022 Aug 12;22:39. doi: 10.1186/s40644-022-00476-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — PFS in the full EP by (A) number of extranodal sites*, (B) bone involvement by PET/CT and (C) baseline bone marrow biopsy and bone involvement by PET/CT, and (D) CNS relapse by the model incorporating imaging metrics and CNS-IPI. *Extranodal involvement was estimated by combining tumor masses in the lungs, liver, spleen, and bone tumor involvement. BMB, bone marrow biopsy; CI, confidence interval; CNS, central nervous system; CNS-IPI, CNS International Prognostic Index; CT, computed tomography; EP, evaluable population; IPI, International Prognostic Index; HR, hazard ratio; PET, positron-emission tomography; PFS, progression-free survival