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. 2022 Aug 12;22:39. doi: 10.1186/s40644-022-00476-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Forest plots for univariate HRs with 95% CIs for (A) investigator-assessed PFS and (B) OS in the training set (n = 846). Involvement was defined as the presence of at least one FDG-avid lesion in the organ or location of interest. CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; FDG, fluorodeoxyglucose; G-CHOP, obinutuzumab plus cyclophosphamide, doxorubicin, vincristine, and prednisone; HR, hazard ratio; IPI, International Prognostic Index; LDH, lactate dehydrogenase; LLN, lower limit of normal; OS, overall survival; PFS, progression-free survival; Q3, third quartile; TMTV, total metabolic tumor volume