Table 3.

Risk of DFR according to PT’s characteristics

	Model 1	Model 2	Model 3
	HR (95% CI), p value
% of the patient follow-up PT	1.00 (0.98–1.02), 0.659	1.00 (0.98–1.02), 0.959
Early PT	1.79 (0.59–5.46), 0.303	3.84 (1.13–13.07), 0.031	3.16 (1.14–8.77), 0.027
Baseline SF-36 physical component score	0.99 (0.96–1.02), 0.47		0.98 (0.96–1.01), 0.136
Cumulative (up to the first 2 years of follow-up) number of DMARDs/patient		0.19 (0.08–0.45), ≤ 0.001	0.12 (0.07–0.41), ≤ 0.001

HR hazard ratio, CI confidence interval, PT persistence on therapy, SF-36 Short Form 36, DMARDs disease-modifying anti-rheumatic drugs