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. 2021 Apr 15;71(4):421–428. doi: 10.1016/j.bjane.2021.02.052

Table 1.

RIFLE, AKIN, and ACOG definitions for AKI.

RIFLE25
Risk 1.5-fold increase in serum creatinine OR 25% decrease in GFR OR < 0.5 mL.kg-1.h-1 for > 6 h
Injury 2-fold increase in serum creatinine OR 50% decrease in GFR OR UO < 0.5 mL.kg-1.h-1 for > 12 h
Failure 3-fold increase in serum creatinine OR 75% decrease in GFR OR UO < 0.3 mL.kg-1.h-1 for > 24 h OR no UO for 12 h
Loss of kidney function Complete loss of kidney function (> 4 weeks)
ESKD Complete loss of kidney function (> 3 months)
AKIN26
Absolute increase in serum creatinine 0.3 mg.dL-1 or more OR 1.5-fold increase in baseline serum creatinine OR UO < 0.5 mL.kg-1.h-1 for > 6 h
ACOG1
Baseline serum creatinine > 1.1 mg.dL-1 OR 2-fold increase in baseline serum creatinine in the absence of renal disease

ESKD, End Stage Kidney Disease; GFR, Glomerular Filtration Rate; UO, Urinary Output.