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. 2021 Apr 15;71(4):421–428. doi: 10.1016/j.bjane.2021.02.052

Table 2.

Intravenous antihypertensive medications used in hypertensive pulmonary edema during preeclampsia.

Drug Starting dose Repeating doses and intervals Maximum total dose Comments
Labetalol42, 66 20 mg 40 mg after 10 minutes 220 mg Avoid in asthma, chronic obstructive airways disease, and heart failure; associated with neonatal bradycardia and hypoglycemia
Hydralazine42, 66 5 mg 5–10 mg after 20 minutes 20 mg Risk of sudden hypotension and maternal tachycardia; may need preloading or simultaneous fluid infusion
Nitroglycerine10, 42, 67, 68 5 μg.min−1 Gradually increase every 3–5 minutes 100 μg.min−1 Considered the drug of choice by some authors; may aggravate the depletion of intravascular volume
Furosemide10 20–40 mg 40–60 mg after 30 minutes 120 mg May worsen placental perfusion