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. 2020 Oct 16;70(6):662–666. doi: 10.1016/j.bjane.2020.10.003

Table 1.

Severity grading of anaphylactic reactions according to Ring and Messmer.

Grade Symptoms
I Skin symptoms and/or mild fever reaction
II Measurable, but not life-threatening
Cardiovascular reaction (tachycardia, hypotension)
Gastrointestinal disturbance (nausea)
Respiratory disturbance
III Shock, life-threatening spasm of smooth muscles (bronchi, uterus)
IV Cardiac and/or respiratory arrest