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. 2021 May 12;72(1):88–94. doi: 10.1016/j.bjane.2021.04.028

Table 2.

Hemodynamic changes measured by pressure recording analytical method.

Variable Group Ti T0 T1 T3 T5 T10 T30 Tdef Tdef5 p
HR (bpm) PCVG 75 ± 9 79 ± 9 82 ± 8 75 ± 10 78 ± 8 77 ± 10 76 ± 8 80 ± 10 83 ± 9 0.093
VC 86 ± 14 80 ± 15 79 ± 13 78 ± 15 83 ± 10 86 ± 13 85 ± 14 82 ± 9 81 ± 10
MAP (mmHg) PCVG 77 ± 13 78 ± 8 77 ± 11 78 ± 11 76 ± 11 77 ± 11 78 ± 11 76 ± 10 76 ± 11 0.916
VC 77 ± 16 78 ± 14 76 ± 14 74 ± 12 74 ± 11 77 ± 13 78 ± 11 75 ± 13 77 ± 18
SVRI
dyne.s.m-2.cm-5 		PCVG 2687 ± 288 2484 ± 244 2548 ± 364 2530 ± 246a 2454 ± 184a 2566 ± 172 2464 ± 245b 2499 ± 246 2506 ± 257 0.317
VC 2669 ± 418 2675 ± 417 2799 ± 541 2852 ± 453 2770 ± 474 2784 ± 597 2668 ± 316 2558 ± 349 2542 ± 527
SVI
mL.m-2 		PCVG 35 ± 9 34.2 ± 7.5a 38.2 ± 7.8 37.6 ± 5.9 34.1 ± 7.7 37.3 ± 9.7 38.9 ± 7.9 39.3 ± 7.7a 37.5 ± 8.6 0.438
VC 30.7 ± 10 24.6 ± 5.8b 31.3 ± 7.1c 32.4 ± 9.2c 32.8 ± 8.8c 33.7 ± 8.9c 34.7 ± 9.1c 30.1 ± 8.5c 32.2 ± 8.3c
CI
L.min-1.m-2 		PCVG 2.56 ± 0.32 2.61 ± 0.22 2.77 ± 0.30 2.75 ± 0.28 2.79 ± 0.31 2.65 ± 0.26 2.69 ± 0.29 2.60 ± 0.28 2.65 ± 0.21 0.025
VC 2.73 ± 0.48 2.86 ± 0.51 2.58 ± 0.45 2.55 ± 0.54 2.62 ± 0.46 2.92 ± 0.69 2.88 ± 0.49 2.64 ± 0.43 2.80 ± 0.57
SVV (%) PCVG 24 ± 21 23 ± 23 23 ± 17 17 ± 8 18 ± 9 19 ± 12 21 ± 18 19 ± 10 19 ± 15 0.144
VC 23 ± 9 21 ± 9b 18 ± 8b 20 ± 8 23 ± 19 32 ± 25 22 ± 11 20 ± 6 18 ± 7b
dP/dt
mmHg.s-1 		PCVG 0.57 ± 0.24 0.55 ± 0.37 0.49 ± 0.34 0.62 ± 0.28 0.62 ± 0.27 0.72 ± 0.25c 0.60 ± 0.35 0.60 ± 0.32 0.68 ± 0.33 0.347
VC 0.51 ± 0.28 0.35 ± 0.27 0.57 ± 0.35 0.58 ± 0.28c 0.48 ± 0.34 0.61 ± 0.29c 0.54 ± 0.29 0.73 ± 0.26b, c 0.62 ± 0.26c
CCE PCVG 0.154 ± 0.79 0.171 ± 0.83 0.169 ± 0.72 0.169 ± 0.71 0.072 ± 0.66 0.084 ± 0.69 0.164 ± 0.81 0.265 ± 0.43 0.305 ± 0.48 0.554
VC 0.039 ± 0.56 -0.131 ± 0.59 0.010 ± 0.52 -0.117 ± 0.66 -0.104 ± 0.47 0.140 ± 0.46 -0.081 ± 0.38 0.238 ± 0.49 -0.041 ± 0.55

Data are expressed as mean ± SD.

Hemodynamic data were measured at anesthesia induction (Ti), at peritoneal insufflation (T0), 1 (T1), 3 (T3), 5 (T5), 10 (T10), and 30 (T30) minutes after CO2 pneumoperitoneum, at desufflation (Tdef) and at termination of pneumoperitoneum (5 minutes after desufflation) (T5def).

HR, Heart Rate; MAP, Mean Arterial Pressure; SVRI, Systemic Vascular Resistance Index; SVI, Stroke Volume Index; CI, Cardiac Index; SVV, Stroke Volume Variation; dP/dt, Aortic pressure variation over time; CCE, Cardiac Cycle Efficiency.

Comparison between the study groups was done using Student t-test for independent samples while within group comparison between the different time points was done using paired sample t-test. Comparison of the different variables over the study time points was done using repeated measure analysis of variance through General Linear Model regression analysis with repeated measure and the paired t-test was done as a post hoc test and are given in the right column of the table. p < 0.05 was considered statistically significant.

a

p < 0.05 between groups at the same time points.

b

p < 0.05 compared with anesthesia induction (Ti).

c

p < 0.05 compared with peritoneal insufflation (T0).