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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Behav Pharmacol. 2022 Aug 3;33(6):418–426. doi: 10.1097/FBP.0000000000000690

Figure 1. Oxycodone increases the percentage of open arm time and the percentage of open arm entries in the elevated plus-maze test.

Figure 1.

Oxycodone increased the percentage of time on the open arms (A) and the percentage of open arm entries (B) in the male and female rats. Compared to the males, the females spent a higher percentage of time on the open arms and had higher percentage open arm entries. Asterisks indicate a higher percentage of time on the open arms compared to the male rats treated with vehicle. *, p<0.05; **, p<0.01; ***, p<0.001. N=10/group. Data are expressed as means ± SEM.