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(A) CHRM3 expression on the sweat gland epithelium of HC and CholU patients’ skin before and after pulse-controlled ergometry (PCE). (B) CHRM3 expression within CholU patients was significantly reduced before PCE provocation in the SRS patient group. (C) A similar trend was seen in the skin samples after provocation, but here no significance level was reached. NS, normal sweating CholU; RS, reduced sweating CholU; SRS, severely reduced sweating CholU.
