FIG. 1.

Features of the primary sequence of S. The predicted sequence of the λ S107 gene product is shown, with shaded bars over the three potential transmembrane domains and a hatched bar above the hydrophilic C-terminal domain characteristic of holins. Shown on the left is a blow-up of the amino-terminal sequences of the S107 and S105 products, including the corresponding mRNA sequence of the translational initiation region and the sdi stem-loop structure (31). Shown on the right is a blow-up of the C-terminal hydrophilic domain, including the corresponding mRNA sequence and, below that, the +1 frameshift mutation of λaj1, isolated as a suppressor of the plaque-forming defect of SA52G (also shown) (21). The time of lysis onset is shown in parentheses for both the SA52G early-lysis mutant and λaj1.