Comparison between the TIIClnc signature and other models. A. The C-index of the TIIClnc signature, other clinical factors, and the combination signature in the TCGA LGG, Xiangya in-house, CGGA LGG, and GSE108474 datasets. B. The 1-year, 2-year, and 3-year calibration curves of the TIIClnc signature in the TCGA LGG, Xiangya in-house, CGGA LGG, and GSE108474 datasets. C. The C-index of the TIIClnc signature and other models developed in the TCGA LGG dataset. D. The C-index of the TIIClnc signature and other models developed in the Xiangya in-house dataset. E. The C-index of the TIIClnc signature and other models developed in the CGGA LGG dataset. F. The C-index of the TIIClnc signature and other models developed in the GSE108474 dataset.