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Effects of SILY-EVs on revascularization in the ischemic hind limb. (A) Representative immunofluorescence staining of CD31 and α-SMA. The arrows indicated the capillaries. Scale bar = 15 μm. Quantification of the density of (B) capillaries and (C) arterioles. Expression of angiogenic genes, (D) ANG II and (E) PECAM1, in different treatment groups. Data are expressed as mean ± standard deviation: *p < 0.05 (n = 6).
