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. 2022 Jul 18;12(13):5710–5726. doi: 10.7150/thno.71832

Figure 2.

Figure 2

cTBS increased the level of DCX positive immature neurons in the peri-infarct area 6 days after PT stroke. (A) (a-d) Demonstrative immunostaining for DCX and BrdU (five daily injections) shows the chains of neuroblasts and individual young neurons in the peri-infarct area. (e-g) Representative images from PT and cTBS groups were processed by surface rendering (e, f) with Bitplane Imaris and the volume of DCX clusters was analyzed, respectively. (h) DCX-positive cells colabeled with BrdU were calculated and compared between groups. (B) (a-c) Immunoreactivity of DCX (green), and NeuN (red) in the peri-infarct zone at day 6. Scale bars represent 50 μm. (c) Numbers of young neurons (DCX+/NeuN+) from brains of the PT control and cTBS groups. Data are the mean ± SE (N =5-8). *P < 0.05 versus Ctl group, #P < 0.05 versus PT group without cTBS.