Table 5.
Prediction Performance on Mortality Based on Main Model With Fructosamine, AlbF, FPG or Not (n = 2 031, without diabetes)
| Model | Model Performance* | ||
|---|---|---|---|
| C-Statistic (95% CI) | IDI (95% CI) | NRI (95% CI) | |
| All-cause mortality | |||
| Main model† | 0.707 (0.699, 0.715) | 0.005 (0.001, 0.013) | 0.067 (0.023, 0.120) |
| +Fructosamine | 0.707 (0.699, 0.716) | 0.004 (0.000, 0.011) | 0.072(0.000, 0.118) |
| +AlbF | 0.710 (0.702, 0.718) | — | — |
| +Albumin +FPG | 0.709 (0.701, 0.717) | 0.003 (0.000, 0.010) | 0.004 (0.000, 0.011) |
| CVD mortality | |||
| Main model† | 0.730 (0.712, 0.748) | 0.000 (−0.001, 0.010) | 0.014 (−0.043, 0.105) |
| +Fructosamine | 0.730 (0.712, 0.748) | 0.000 (−0.001, 0.006) | 0.038 (−0.052, 0.123) |
| +AlbF | 0.730 (0.712, 0.748) | — | — |
| +Albumin +FPG | 0.730 (0.712, 0.748) | 0.001 (−0.001, 0.013) | 0.107 (−0.130, 0.207) |
| Non-CVD mortality | |||
| Main model† | 0.719 (0.708, 0.730) | 0.005 (0.000, 0.013) | 0.082 (0.011, 0.140) |
| +Fructosamine | 0.719 (0.708, 0.730) | 0.004 (0.000, 0.011) | 0.093(0.000, 0.150) |
| +AlbF | 0.723 (0.712, 0.733) | — | — |
| +Albumin +FPG | 0.722 (0.711, 0.733) | 0.003 (0.000, 0.012) | 0.077 (−0.035, 0.133) |
Notes: AlbF = albumin-corrected fructosamine; FPG = fasting plasma glucose; BMI = body mass index; CKD = chronic kidney disease; ADL = activities of daily living; TC = total cholesterol; HDL = high-density lipoprotein; TG = triglycerides; MDA = malondialdehyde; SOD = superoxide dismutase; BUN = blood urea nitrogen; hs-CRP = high-sensitivity C-reactive protein; UA = blood uric acid; CI = confidence interval; CVD = cardiovascular disease; IDI = integrated discrimination improvement; NRI = net reclassification improvement.
*C-statistics were calculated in main models and models further adjusted for different glycemic markers, respectively; NRI and IDI were calculated between models with AlbF to measure the added predictive values to models without AlbF, with fructosamine, or with FPG and albumin.
†Adjusted for age, sex, race, residence, living arrangement, education level, marital status, income level, insurance, smoking, alcohol drinking, exercise, dietary diversity, BMI, hypertension, HD, cerebrovascular disease, anemia, respiratory diseases, CKD, cancer, psychological resources, ADL disability, cognitive impairment, visual function, pain, TC, TG, HDL, MDA, SOD, plasma 25(OH)D, vitamin B12, BUN, hs-CRP, and UA.