Table 3.

Joinpoint analysis for ischemic heart diseases mortality trends in men in the sub regions of the Region of the Americas 2000–2019.

SUB REGION	TOTAL STUDY PERIOD	PERIOD 1		PERIOD 2		PERIOD 3
	AAPC (95% CI)	YEARS	APC (95% CI)	YEARS	APC (95% CI)	YEARS	APC (95% CI)
Region of the Americas	–2.3* (–2.5, –2.1)	2000–2007	–3.5* (–3.8, –3.3)	2007–2012	–2.3* (–2.9, –1.7)	2012–2019	–1.0* (–1.2, –0.7)
North America	–3.0* (–3.1, –2.8)	2000–2011	–4.3* (–4.5, –4.2)	2011–2019	–1.0* (–1.3, –0.7)
Central America, Mexico and Latin Caribbean	0.4* (0.1, 0.7)	2000–2007	–0.8* (–1.5, –0.1)	2007–2019	1.1* (0.7, 1.4)
Andean Area	–1.0* (–1.1, –0.9)
Southern Cone and Brazil	–2.4* (–2.5, –2.2)
Non-Latin Caribbean*	–1.3* (–2.4, –0.2)	2000–2009	–1.3* (–2.0, –0.7)	2009–2012	–3.9 (–10.6, 3.3)	2012–2019	–0.1 (–1.1, 0.9)

AAPC, average annual percent change; APC, annual percent change; CI, confidence interval. * P < 0.05 for change in trend.