Figure 2.

Significant associations between serum levels of soluble markers of B cell activation and SSc characteristics related to PH, assessed among the 80 SSc patients from the discovery cohort. BAFF, B-cell-activating factor; DLCO, diffusing capacity of the lung for carbon monoxide; Ig, immunoglobulin; Nt-pro-BNP, N-terminal prohormone of brain natriuretic peptide; OR, odds ratio; PH, pulmonary hypertension; RF, rheumatoid factor; SSc, systemic sclerosis; TRV, tricuspid regurgitation velocity. Error bars display means and standard deviations. p-values are adjusted for age, gender and immunosuppressive drugs.