Table 3.

RFS of HCC at different RNF125 levels.

Clinicopathological index	Subgroup	Cut off value	Grouping (cases)		Median RFS (months)		HR value	P value
			LEG	HEG	LEG	HEG
	Entire queue	599	229	87	21.93	42.87	0.62(0.42-0.92)	0.0154
Stage	Stage 1	155	37	116	30.1	56.67	0.51(0.29-0.91)	0.021
	Stage 2	568	55	20	6.97	8.4	0.65(0.28-1.51)	0.3116
	Stage 3	196	31	39	7.3	14.33	0.63(0.35-1.16)	0.1326
Grade	Grade 1	736	29	16	8.83	18.87	0.46(0.15-1.4)	0.16
	Grade 2	321	66	83	17.9	30.4	0.56(0.34-0.91)	0.0172
	Grade 3	436	79	28	25.87	10.4	1.47(0.84-2.6)	0.1776
Vascular invasion	None	200	51	124	37.23	42.63	0.75(0.45-1.25)	0.2672
	Micro	519	60	22	13.33	37.67	0.46(0.02-1.05)	0.0593
Gender	Male	590	155	55	21.87	42.63	0.66(0.41-1.05)	0.0804
	Female	147	29	77	11.83	55.87	0.52(0.28-0.97)	0.036
Race	White	674	108	39	16.3	36.1	0.54(0.3-0.96)	0.0325
	Asian	158	52	93	15.97	54.33	0.52(0.31-0.87)	0.0119
Sorafenib treatment		746	14	8	6.33	16.6	0.33(0.12-0.97)	0.036
Alcohol consumption	Yes	259	40	59	13.33	36.1	0.7(0.39-1.26)	0.2321
	None	171	65	118	15.17	42.63	0.6(0.38-0.94)	0.0231
Hepatitis virus	Yes	405	87	52	25.13	42.63	0.68(0.4-1.16)	0.1598
	None	124	35	108	8.7	34.4	0.51(0.29-0.89)	0.0166