TABLE 1.

Cell sources for regenerative central nervous system (CNS) therapy.

Source of cells	Accessibility	Ethical concerns	Tumorigenic	Autologous	Nervous system-derived
NSPCs	Low	Moderate	Sometimes	Sometimes	Yes
ESCs	Low	Significant	Yes	No	No
iPSCs	High	None	Yes	Yes	No
MSCs	High	None	No	Yes	No
HSCs	High	None	No	Yes	No
DPSCs	High	None	No	Yes	No
ENSCs	High	None	No	Yes	Yes
SAT-NSCs	High	None	No	Yes	Yes

NSPCs, neural stem/progenitor cells; ESCs, embryonic stem cells; iPSCs, induced pluripotent stem cells; MSCs, mesenchymal stem cells; HSCs, hematopoietic stem cells; DPSCs, dental pulp stem cells; ENSCs, enteric neuronal stem cells; SAT-NSCs, subcutaneous adipose tissue–neural stem cells.