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(A) Volcano plot shows the transcripts in aged podocytes that were decreased (blue circles), increased (red circles), or not changed (gray circles) by treatment of mice with aPD1ab for 8 weeks. (B) Summary of the number of genes upregulated and downregulated in podocytes from aged control IgG2a mice compared with young mice, and from aged aPD1ab-injected mice compared with age-matched IgG2a-injected mice.
