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. 2022 Aug 1;61(3):112. doi: 10.3892/ijo.2022.5402

Table I.

Relationship between HHLA2 expression and clinical characteristics in patients with gall bladder cancer (N=89).

Parameter Total HHLA2 expression
P-value
Low High
Patients (n) 89 44 45
Sex 0.244
 Male 37 21 16
 Female 52 23 29
Age (years) 0.899
 <62 49 24 25
 ≥62 40 20 20
Differentiation 0.219
 Poorly or moderately 21 13 8
 Well 48 22 26
Nevin stage 0.014
 I-III 37 24 13
 IV-V 52 20 32
American Joint Committee on Cancer stage 0.007
 I-II 36 24 12
 III-IV 53 20 33
Tumor invasion
 T1-T2 44 27 17 0.026
 T3-T4 45 17 28
Regional node metastasis
 Absent 46 29 17 0.018
 Present 31 11 20
Distant metastasis
 Absent 61 34 27 0.079
 Present 28 10 18

HHLA2, human endogenous retrovirus-H long terminal repeat-associating protein 2.