Table 2.
Clinical Symptoms of Respiratory Episodes
| Patient-Reported Symptoms | RSV-ARTI Episodes (n = 36) |
Influenza-ARTI Episodes (n = 57) |
Other ARTI Episodes (n = 657) |
|---|---|---|---|
| Rhinitis | 36 (100) | 55 (96) | 624 (95) |
| Cough | 35 (97) | 55 (96) | 572 (87) |
| Wheeze | 16 (44) | 26 (46) | 223 (34) |
| Phlegm | 34 (94) | 52 (91) | 466 (71)** |
| Dyspnea | 24 (67) | 42 (74) | 309 (47)* |
| Fever (≥38°C) | 2 (6) | 11 (19) | 26 (4) |
| Feeling feverish | 12 (33) | 37 (65)** | 191 (29) |
| Headache | 27 (75) | 45 (79) | 348 (53)* |
| Myalgia | 19 (53) | 41 (72) | 263 (40) |
| Disturbed sleep | 26 (72 | 51 (89)* | 440 (67) |
| Feeling unwell | 33 (91) | 56 (98) | 499 (76)* |
| Disturbance in daily activity | 27 (75) | 51 (89) | 348 (53)** |
| Vital signs from home visita | |||
| Temperature baseline, mean (SD) | 36.4°C (0.5) | 36.4°C (0.7) | 36.5°C (0.6) |
| Temperature ARTI, mean (SD) | 36.6°C (0.6) | 36.9°C (1.0)* | 36.5°C (0.6) |
| Temperature increase, mean (SD)b | 0.2°C (0.6) | 0.5°C (0.8) | 0°C (0.7) |
| Fever, ≥38°C | 2 (6) | 9 (16) | 13 (2) |
| Respiratory rate/min, mean (SD) | 17 (5) | 17 (5) | 17 (4) |
| Respiratory rate > 20/min | 6 (17) | 8 (14) | 63 (10) |
| Saturation, mean (SD) | 96% (2) | 96% (2) | 97% (2)* |
| Saturation, SaO2 < 95% | 5 (14) | 10 (18) | 39 (6) |
| Heart rate, bpm, mean (SD) | 74 (12) | 76 (12) | 71 (11) |
| Composite fever, ≥38°Cc | 4 (11) | 14 (25) | 33 (5) |
Data are No. (%) except where indicated. Numbers represent respiratory episodes unless stated otherwise.
Abbreviations: ARTI, acute respiratory tract infection; bpm, beats per minute; RSV, respiratory syncytial virus.
Statistical significance compared to RSV-ARTI: *P < .05, **P < .01, ***P < .001 (not indicated if nonsignificant).
aMeasured by the study team during the ARTI visit unless otherwise indicated.
bCompared to baseline measurement before the season.
cPatient reported or measured during ARTI home visit.