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. 2022 Aug 12;12:13705. doi: 10.1038/s41598-022-18016-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Current perception thresholds under non-noxious condition. Differences in the mean value of current perception thresholds before and after non-noxious stimulation. The error bars indicate standard deviation. No significant changes are observed in the current perception thresholds of the Aδ and C fibers when the dorsal side of the forearm was lightly rubbed with a brush. A significant increase in the threshold of the Aβ fibers is observed. Asterisks represent significant differences (*P < 0.0083).