Table 5.
Parameters of various release kinetic models.
Release kinetic models | Formulations | Parameters | ||
---|---|---|---|---|
Slope | Intercept | r2 | ||
Zero order | Pure drug | 0.0296 | 18.769 | 0.4996 |
SFB-loaded ME | 0.055 | 20.834 | 0.662 | |
SFB-marketed formulation | 0.0124 | 4.9346 | 0.4992 | |
First order | Pure drug | 0.007 | 1.067 | 0.256 |
SFB-loaded ME | 0.0009 | 1.07 | 0.334 | |
SFB-marketed formulation | 0.0007 | 0.5248 | 0.4308 | |
Higuchi | Pure drug | 0.565 | 3.004 | 0.754 |
SFB-loaded ME | 0.379 | 1.361 | 0.889 | |
SFB-marketed formulation | 1.3215 | 0.8616 | 0.7364 |