Table 6.

Various pharmacokinetic parameters of ME16 and free SFB.

Parameters	Unit	SFB-loaded ME	Free SFB
V/F	(mg)/(μg/ml)	1.08	1.30
CL/F	(mg)/(μg/ml)/h	0.05	0.09
Tmax	h	4.02	4.70
Cmax	μg/ml	625.31	456.47
AUC 0-t	μg/ml h	12,686.98	8238.03
AUC 0-inf	μg/ml h	15,550.59	9113.58
MRT	h	21.82	16.49