Table 3.

Diagnostic values of has_circ_0006423, miR-492 and 3 traditional lung cancer markers.

Item	AUC	Sensitivity	Specificity
Pre-op versus Healthy (hsa_circ_0006423)	0.865	0.817	0.793
Pre-op versus Healthy (miR-492)	0.883	0.817	0.842
Post-op versus Healthy (hsa_circ_0006423)	0.766	0.744	0.707
Post-op versus Healthy (miR-492)	0.694	0.451	0.927
Pre-op versus Post-op (hsa_circ_0006423)	0.725	0.860	0.598
Pre-op versus Post-op (miR-492)	0.767	0.573	0.866
Cancer versus Adjacent (hsa_circ_0006423)	0.883	0.915	0.720
Cancer versus Adjacent (miR-492)	0.954	0.890	0.866
Combination	0.992	0.915	0.882
NSE	0.619	0.733	0.567
CYFR21-1	0.586	0.633	0.633
CA72-4	0.521	0.867	0.367

NSE neuron-specific enolase, CYFR21-1 cytokeratin-19-fragment, CA72-4 cancer antigen 72-4.