Table 5.
Summary of Bleeding Index over time
Time point | Mean Bleeding Index (±SD) | Between Treatment Comparison* | |||
---|---|---|---|---|---|
0.1% o-cymen-5-ol/ 0.6%ZnCl2 (N = 112) | 0.204% Sodium Fluoride (N = 112) | Mean Difference (%) | 95% CI | P-value | |
Pre-Prophy Baseline | 0.63 ± 0.250 | 0.64 ± 0.227 | |||
Randomisation | 0.20 ± 0.110 | 0.20 ± 0.101 | |||
Week 6 | 0.29 ± 0.144 | 0.35 ± 0.141 | −0.06 (−18.5%) | (−0.08, −0.04) | <0.0001 |
Week 12** | 0.13 ± 0.075 | 0.20 ± 0.100 | −0.09 (−37.8%) | (−0.11, −0.07) | <0.0001 |
0.1% w/w o-cymen-5-ol/ 0.6%w/w zinc chloride (ZnCl2) dentifrice vs 0.204%w/w sodium fluoride dentifrice, a negative difference favours the experimental dentifrice. Comparison based on model-adjusted means. Difference based on transformed values (square root transformation).
N = 104 and N = 101 were assessed in each group respectively at Week 12.