Table 3.

Details of accepted studies: number at baseline; number evaluated; number of events; means, and loss to follow-up

Study	DS	Xylitol group						Sorbitol group
		BL	N	n	Mean	SD	LtF	BL	N	n	Mean	SD	LtF
Milgrom et al.20	01	35	33	Nil	0.6	1.1	2	32	29	Nil	1.9	2.4	3
	02	33	32	Nil	1	1.4	1	32	29	Nil	1.9	2.4	3
Mäkinen et al.21	03	60	37	Nil	0.01	3.4	23	65	33	Nil	0.6	5.7	32
Mäkinen et al.22	04	125	95	Nil	−0.8	0.5	30	129	120	Nil	3.8	0.4	9
Mäkinen et al.26	07	Nil	75	10	Nil	Nil	Nil	Nil	157	17	Nil	Nil	Nil
	08	Nil	120	32	Nil	Nil	Nil	Nil	157	17	Nil	Nil	Nil
	09	Nil	133	20	Nil	Nil	Nil	Nil	157	17	Nil	Nil	Nil
	10	Nil	176	43	Nil	Nil	Nil	Nil	157	17	Nil	Nil	Nil
Mäkinen et al.26	11	Nil	337	94	Nil	Nil	Nil	Nil	571	85	Nil	Nil	Nil
	12	Nil	529	138	Nil	Nil	Nil	Nil	705	108	Nil	Nil	Nil
Mäkinen et al.23	05	Nil	36	Nil	15.5	1.08*	Nil	Nil	60	Nil	20.67	0.62*	Nil
	06	Nil	90	Nil	24.2	0.48*	Nil	Nil	63	Nil	36.4	0.72*	Nil
Hujoel et al.27	13	Nil	2,746	32	Nil	Nil	Nil	Nil	4,129	87	Nil	Nil	Nil
	14	Nil	5,234	72	Nil	Nil	Nil	Nil	4,088	83	Nil	Nil	Nil
Machiulskiene et al.24	15	126	107	Nil	5.5	0.52†	19	118	105	Nil	3	0.45†	13
	16	126	99	Nil	8.1	0.62†	27	118	68	Nil	9	0.80†	50
	17	125	99	Nil	3.2	0.3†	26	114	71	Nil	3.4	0.48†	43
Mäkinen et al.25	18	41	41	Nil	2.6	0.55*	0	42	42	Nil	13.7	2.64*	0

^*SD calculated from 95% confidence interval (asymmetric).

^†SD calculated from 95% confidence interval (symmetric).

DS, dataset number; BL, number at baseline; N, number evaluated; n, number of events; SD, standard deviation; LtF, lost to follow-up; Nil, no information provided.