Table 3.
Treatment comparisons of the effect of dentifrice quantity, duration of brushing, rinsing regimen and concentration of F− in the dentifrice on expectorate, rinse, toothbrush washings, and the amount of fluoride delivered to the oral cavity (using adjusted means). The difference is first-named treatment minus second-named treatment, such that a positive difference favours the first-named treatment
| Comparison | Expectorate | Rinse | Toothbrush washings | Amount of F− delivered to oral cavity | ||||
|---|---|---|---|---|---|---|---|---|
| Difference, μg (95% CI*) | P-value | Difference, μg (95% CI*) | P-value | Difference, μg (95% CI*) | P-value | Difference, μg (95% CI*) | P-value | |
| 120 seconds versus 45 seconds (0.5 g 1 × 15 ml, 1,150 ppm F) | 85.49 (12.9, 158.1) | 0.0211 | −25.94 (−51.5, −0.4) | 0.0465 | −86.33 (−117.7, −54.9) | <0.0001 | −3.09 (−76.9, 70.7) | 0.9344 |
| 120 seconds versus 45 seconds (1.5 g 1 × 15 ml, 1,150 ppm F) | 324.09 (250.9, 397.3) | <0.0001 | −80.97 (−106.7, −55.3) | <0.0001 | −156.64 (−187.8, −125.5) | <0.0001 | −112.24 (−185.1, −39.4) | 0.0026 |
| 1.5 g versus 0.5 g (45 seconds 1 × 15 ml, 1,150 ppm F) | 479.61 (404.8, 554.4) | <0.0001 | 149.37 (123.4, 175.3) | <0.0001 | 163.66 (132.2, 195.1) | <0.0001 | 460.58 (385.7, 535.5) | <0.0001 |
| 1.5 g versus 0.5 g (60 seconds 1 × 15 ml, 1,150 ppm F) | 548.73 (475.1, 622.4) | <0.0001 | 142.32 (116.6, 168.1) | <0.0001 | 184.94 (153.7, 216.2) | <0.0001 | 402.40 (329.2, 475.6) | <0.0001 |
| 1.5 g versus 0.5 g (120 seconds 1 × 15 ml, 1,150 ppm F) | 718.22 (647.2, 789.3) | <0.0001 | 94.34 (69.0, 119.7) | <0.0001 | 93.36 (62.1, 124.6) | <0.0001 | 351.43 (279.6, 423.3) | <0.0001 |
| 1.5 g versus 0.5 g (45–120 seconds, 1,150 ppm F) | 582.19 (539.8, 624.6) | <0.0001 | 128.68 (113.8, 143.5) | <0.0001 | 147.32 (129.2, 165.4) | <0.0001 | 404.81 (362.4, 447.3) | <0.0001 |
| 1,150 ppm F versus 250 ppm F (60 seconds 1.5 g, 1 × 15 ml) | 667.11 (591.9, 742.3) | <0.0001 | 166.44 (140.6, 192.3) | <0.0001 | 245.74 (214.4, 277.1) | <0.0001 | 415.03 (340.3, 489.8) | <0.0001 |
| 1 × 15 ml versus 3 × 15 ml rinses (60 seconds 1.5 g, 1,150 ppm F) | 29.20 (−44.6, 103.0) | 0.4367 | −131.55 (−157.3, −105.8) | <0.0001 | 47.57 (16.3, 78.8) | 0.0030 | 11.12 (−62.2, 84.4) | 0.7656 |
*
Confidence intervals for the treatment difference between the true means of the two treatments being compared. Significant differences are in bold type.