Table 2.
Univariate and Multivariate analysis.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Estimated | St error | P-value | Estimated | St error | P-value | |
| Univariate and multivariate analysis for SARS-CoV-2–specific IgG | ||||||
| Group [Reference CG] | ||||||
| MGUS | 0.041 | 0.193 | 0.832 | 0.152 | 0.197 | 0.444 |
| SMM | −0.056 | 0.170 | 0.744 | 0.219 | 0.230 | 0.343 |
| MM | −1.016 | 0.225 | <0.0001 | −0.686 | 0.287 | 0.019 |
| Sex (Woman) | −0.119 | 0.156 | 0.446 | |||
| Age | −0.016 | 0.005 | 0.002 | −0.013 | 0.005 | 0.007 |
| Gammopathy subtype | ||||||
| IgG (Kappa or Lambda) | −0.337 | 0.176 | 0.059 | |||
| IgA (Kappa or Lambda) | 0.129 | 0.250 | 0.607 | |||
| IgM (Kappa or Lambda) | −0.281 | 0.308 | 0.364 | |||
| Bence Jones Kappa | −0.242 | 0.508 | 0.635 | |||
| Bence Jones Lambda | −0.446 | 0.708 | 0.530 | |||
| Immunoparesis | −0.438 | 0.153 | 0.005 | −0.245 | 0.213 | 0.253 |
| Days post-complete schedule | −0.003 | 0.002 | 0.117 | |||
| Vaccine kind (Moderna) | 0.157 | 0.161 | 0.335 | |||
| Univariate and multivariate analysis for SARS-CoV-2–specific IgA | ||||||
| Group [Reference CG] | ||||||
| MGUS | −0.089 | 0.176 | 0.617 | 0.038 | 0.181 | 0.834 |
| SMM | −0.183 | 0.155 | 0.242 | 0.125 | 0.211 | 0.557 |
| MM | −0.735 | 0.205 | <0.001 | −0.370 | 0.263 | 0.164 |
| Sex (Woman) | −0.080 | 0.135 | 0.555 | |||
| Age | −0.012 | 0.004 | 0.004 | −0.009 | 0.004 | 0.030 |
| Gammopathy subtype | ||||||
| IgG (Kappa or Lambda) | −0.316 | 0.151 | 0.040 | |||
| IgA (Kappa or Lambda) | −0.087 | 0.214 | 0.686 | |||
| IgM (Kappa or Lambda) | −0.374 | 0.264 | 0.161 | |||
| Bence Jones Kappa | 0.079 | 0.436 | 0.856 | |||
| Bence Jones Lambda | −0.890 | 0.608 | 0.147 | |||
| Immunoparesis (yes) | −0.436 | 0.130 | 0.001 | −0.317 | 0.195 | 0.109 |
| Days post-complete schedule | −0.002 | 0.002 | 0.280 | |||
| Vaccine kind (Moderna) | 0.202 | 0.139 | 0.151 | |||
| Univariate and multivariate analysis for neutralization | ||||||
| Group [Reference CG] | ||||||
| MGUS | 0.010 | 0.129 | 0.941 | 0.003 | 0.108 | 0.979 |
| SMM | −0.040 | 0.114 | 0.725 | −0.105 | 0.138 | 0.449 |
| MM | −0.415 | 0.150 | 0.007 | −0.507 | 0.173 | 0.005 |
| Sex (Woman) | −0.078 | 0.099 | 0.433 | |||
| Age | −0.013 | 0.003 | <0.0001 | −0.009 | 0.003 | 0.001 |
| Gammopathy subtype | ||||||
| IgG (Kappa or Lambda) | −0.104 | 0.113 | 0.362 | |||
| IgA (Kappa or Lambda) | 0.055 | 0.161 | 0.734 | |||
| IgM (Kappa or Lambda) | −0.187 | 0.198 | 0.346 | |||
| Bence Jones Kappa | −0.104 | 0.326 | 0.749 | |||
| Bence Jones Lambda | −0.331 | 0.455 | 0.453 | |||
| Immunoparesis (yes) | −0.203 | 0.097 | 0.040 | 0.043 | 0.118 | 0.721 |
| Days post-complete schedule | −0.004 | 0.001 | <0.0001 | −0.005 | −0.005 | <0.0001 |
| Vaccine kind (Moderna) | 0.167 | 0.102 | 0.107 | 0.258 | 0.093 | 0.007 |
Significant P-values are indicated in bold and all P-values are in italic.