Table 4.
Results of histopathologic analysis of lesions and distribution NDV in tissues of ECE.
| Tissue | Necrosis | Hemorrhage | Inflammatory cell infiltration | Distribution/expression | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| A | B | C | D | A | B | C | D | A | B | C | D | A | B | C | D | |
| Brain | +++ | - | - | - | +++ | + | + | - | ++ | - | - | - | ++/++ | ++/++ | - | - |
| Trachea | ++ | + | + | - | ++ | + | ++ | - | ++ | ++ | +++ | - | +++/+++ | +++/+++ | +++/+++ | - |
| Lungs | +++ | + | + | - | +++ | + | + | - | +++ | + | + | - | +++/+++ | +++/+ | +++/+++ | - |
| Proventriculus | +++ | + | + | - | ++ | + | ++ | - | ++ | + | ++ | - | +++/+++ | +++/++ | ++/+++ | - |
| Intestinum | +++ | + | - | - | ++ | + | + | - | ++ | + | - | - | +++/+++ | +++/+++ | - | - |
| Heart | + | - | - | - | +++ | ++ | ++ | - | ++ | - | - | - | +++/+++ | ++/++ | - | - |
| Kidney | +++ | - | ++ | - | +++ | + | ++ | - | +++ | + | + | - | +++/+++ | +++/++ | ++/++ | - |
| Liver | ++ | ++ | - | - | +++ | ++ | ++ | - | ++ | - | - | - | +++/+++ | +++/+++ | - | - |
| Skin | +++ | - | - | - | +++ | + | + | - | +++ | - | - | - | +++/+++ | +++/+++ | - | - |
NDV = Newcastle disease virus, A = NDV Velogenic, B = NDV Lentogenic, C = NDV vaccine strain LaSota and D = Negative control. Lesion (+) = focal, (++) = multifocal, and (+++) = diffuse. IHC staining (+) = low, (++) = moderate, and (+++) = severe