Table 1.
Demographic, clinical characteristics and laboratory findings of SFTS patients
| Characteristics | Recovered (n = 8) | Deceased (n = 3) | p-value |
|---|---|---|---|
| Epidemiology, no. (%) | |||
| Age, mean Y ± SD (range) | 71.0 ± 12.4 | 69.3 ± 11.02 | 0.8429 |
| Female | 4 (50.0) | 2 (66.7) | 0.9103 |
| Occupational exposure | 3 (37.5) | 1 (33.3) | 0.6618 |
| Comorbidities, no. (%) | |||
| Cardiovascular disease* | 1 (12.5) | 0 | 0.5683 |
| Cerebrovascular disease | 1 (12.5) | 0 | 0.5683 |
| Pulmonary disease** | 0 | 0 | – |
| Chronic kidney disease | 0 | 0 | – |
| Diabetes mellitus | 1 (12.5) | 0 | 0.5683 |
| Malignancies | 0 | 0 | – |
| Clinical signs and symptoms, no. (%) | |||
| Headache | 2 (25.0) | 1 (33.3) | 0.8075 |
| Dyspepsia | 5 (62.5) | 2 (66.7) | 0.9103 |
| Nausea/vomiting | 5 (62.5) | 1 (33.3) | 0.4385 |
| Abdominal pain | 5 (62.5) | 0 | 0.0738 |
| Chills | 6 (75.0) | 3 (100) | 0.3893 |
| Myalgia | 5 (62.5) | 2 (66.7) | 0.9103 |
| Fatigue | 7 (87.5) | 1 (33.3) | 0.4761 |
| Rash/Eschar | 3 (37.5) | 1 (33.3) | 0.9103 |
| Tick bite | 6 (75.0) | 1 (33.3) | 0.2413 |
| Laboratory values, median (IQR) | |||
| WBC count, × 1000/mm3 | 2276.3 (1150–4150) | 1866.7 (1240–2400) | 0.5659 |
| Platelet count, × 1000/mm3 | 57,125 (25,000–93,000) | 33,000 (21,000–45,000) | 0.1286 |
| aPTT, sec | 40.9 (33.6–52.4) | 84.4 (78.5–90.9) | < 0.001 |
| Total bilirubin, mg/dL | 1.5 (0.58–5.13) | 2 (1.08–2.5) | 0.5740 |
| Albumin, g/dL | 3.2 (2.8–3.5) | 2.5 (1.9–2.9) | < 0.001 |
| AST, IU/L | 337.4 (71–1210) | 6670.7 (4710–9956) | < 0.001 |
| ALT, IU/L | 121.8 (46–242) | 1096.3 (846–1366) | < 0.001 |
| LD, IU/L | 1562.6 (775–3082) | 16,619.7 (14,915–18,030) | < 0.001 |
| Creatinine, mg/dL | 0.9 (0.44–1.28) | 2.4 (2.22–2.8) | < 0.001 |
| hs-CRP, mg/dL | 9.5 (1.15–22.4) | 34 (32.33–36.31) | < 0.001 |
| Ct value | |||
| S segment | 31.1 (23.56–36.88) | 25.4 (21.16–31.5) | 0.0805 |
| M segment | 30.1 (22.26–33.65) | 26.8 (22.26–33) | 0.2839 |
SFTS severe fever with thrombocytopenia syndrome; SD standard deviation; IQR, interquartile range; WBC white blood cell; aPTT activated partial thromboplastin time; AST aspartate aminotransferase; ALT alanine aminotransferase; LD lactate dehydrogenase; CRP C-reactive protein
*Includes myocardial infarction, congestive heart failure, and peripheral vascular disease
**Chronic obstructive pulmonary disease, asthma
Statistically significant values are shown in bold