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. 2022 Jul 29;11(15):e023690. doi: 10.1161/JAHA.121.023690

Table 2.

Distribution of Cardiovascular Risk Factors of the Study Population According to the LDL‐C Level

Risk factors LDL‐C levels P value
<70 mg/dL 70–99.9 mg/dL 100–129.9 mg/dL 130–159.9 mg/dL 160–189.9 mg/dL ≥190 mg/dL
CRP, % <0.001
0.00–2.99 mg/L 78.85 (2.52) 79.63 (1.31) 73.81 (1.41) 69.88 (1.62) 68.04 (2.28) 67.38 (3.05)
≥3.00 mg/L 19.75 (2.51) 19.37 (1.31) 25.36 (1.47) 29.09 (1.72) 31.28 (2.26) 31.50 (3.08)
BMI categories, % <0.001
<25.0 62.57 (3.01) 64.30 (1.37) 50.13 (1.35) 35.92 (1.60) 28.86 (1.92) 33.17 (2.60)
25.0–29.9 26.16 (2.86) 22.60 (1.33) 28.33 (1.19) 37.55 (1.26) 46.08 (1.98) 39.78 (1.95)
≥30.0 11.25 (1.52) 13.05 (0.93) 21.49 (1.35) 26.42 (1.26) 24.91 (1.44) 27.00 (2.70)
Hypertension, % 20.34 (2.51) 23.34 (1.15) 32.85 (1.30) 46.40 (1.36) 54.48 (2.14) 53.81 (3.17) <0.001
SBP, mm Hg 115.21 (0.68) 115.36 (0.38) 119.09 (0.57) 123.41 (0.41) 126.44 (0.65) 129.70 (0.92) <0.001
DBP, mm Hg 69.27 (0.58) 71.02 (0.30) 73.12 (0.28) 75.49 (0.28) 76.74 (0.35) 77.14 (0.56) <0.001
Pulse pressure, mm Hg 45.95 (0.68) 44.33 (0.43) 45.96 (0.48) 47.92 (0.37) 49.70 (0.55) 52.55 (0.78) 0.003
Diabetes, % 7.12 (1.99) 4.43 (0.54) 6.66 (0.47) 8.24 (0.69) 8.15 (0.75) 8.39 (1.53) 0.001
Fasting glucose, mg/dL 97.59 (3.78) 93.07 (0.66) 95.88 (0.61) 98.87 (0.64) 98.92 (0.72) 101.65 (1.38) 0.575
Respiratory diseases, % 0.887
Yes 13.72 (2.41) 11.00 (0.81) 11.83 (0.70) 12.09 (0.92) 11.85 (1.33) 11.54 (2.13)
No 86.28 (2.41) 89.00 (0.81) 88.17 (0.70) 87.91 (0.92) 88.15 (1.33) 88.46 (2.13)
Liver diseases, % 0.013
Yes 35.49 (4.57) 27.73 (1.54) 30.76 (1.67) 34.80 (1.80) 35.80 (2.40) 33.50 (4.00)
No 64.51 (4.57) 72.27 (1.54) 69.24 (1.67) 65.20 (1.80) 64.20 (2.40) 66.50 (4.00)
Chronic kidney disease, % 5.95 (0.99) 7.95 (0.72) 10.52 (0.74) 16.19 (0.99) 22.33 (1.43) 27.12 (2.37) <0.001
eGFR, mL/min per 1.73 m2 85.73 (1.08) 82.74 (0.58) 79.14 (0.54) 75.58 (0.54) 72 (0.64) 69.9 (0.91) <0.001
Cholesterol‐lowering drugs, % <0.001
Yes 0.17 (0.14) 0.53 (0.22) 1.37 (0.30) 3.08 (0.42) 4.80 (0.63) 4.05 (0.93)
No 99.83 (0.14) 99.47 (0.22) 98.63 (0.30) 96.92 (0.42) 95.20 (0.63) 95.95 (0.93)

Values are means (SE) for continuous variables or percentages (SE) for categorical variables and are weighted except No. of participants. Numbers may not add to 100% due to missing data. BMI indicates body mass index; CRP, C‐reactive protein; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; LDL‐C, low‐density lipoprotein cholesterol; and SBP, systolic blood pressure.