Table 4.
Hazard Ratio, Adjusted Hazard Ratio, and 95% Confidence Intervals of the Variables Using Univariate and Multivariable Cox PH Regression
| Variable | HR (95% CI) | p-valuea | Adj. HR (95% CI) | p-valueb |
|---|---|---|---|---|
| Age at diagnosis | ||||
| <40r | 1.00 | - | 1.00 | - |
| 40-49 | 4.50 (1.65-12.3) | 0.003* | 2.04 (0.69-5.99) | 0.193 |
| 50-59 | 8.62 (3.36-22.1) | <0.001* | 4.97 (1.87-13.22) | 0.001* |
| 60-69 | 8.65 (3.04-24.67) | <0.001* | 3.05 (0.99-9.39) | 0.052 |
| ≥70 | 9.62 (3.34-27.72) | <0.001* | 4.06 (1.30-12.64) | 0.016* |
| District | ||||
| Brunei Muarar | 1.00 | - | ||
| Tutong | 0.86 (0.46-1.61) | 0.636 | ||
| Belait | 0.48 (0.21-1.11) | 0.084 | ||
| Temburong | 0.00 (0.00-∞) | 0.995 | ||
| Ethnicity | ||||
| Malayr | 1.00 | - | ||
| Chinese | 0.43 (0.16-1.18) | 0.101 | ||
| Others | 0.68 (0.25-1.87) | 0.460 | ||
| Stage | ||||
| Localizedr | 1.00 | - | 1.00 | - |
| Regional | 9.51 (3.67-24.63) | <0.001* | 6.60 (2.43-17.92) | <0.001* |
| Distant | 13.72 (5.39-34.92) | <0.001* | 10.80 (4.03-28.94) | <0.001* |
| Histology | ||||
| Serous carcinomar | 1.00 | - | 1.00 | - |
| Mucinous carcinoma | 0.51 (0.26-1.00) | 0.051 | 1.66 (0.79-3.49) | 0.182 |
| Endometrioid carcinoma | 0.96 (0.43-2.16) | 0.925 | 1.35 (0.58-3.17) | 0.490 |
| Clear cell carcinoma | 0.70 (0.21-2.35) | 0.568 | 0.97 (0.28-3.39) | 0.963 |
| Undifferentiated or other-epithelial | 1.99 (1.15-3.46) | 0.015* | 2.10 (1.14-3.87) | 0.017* |
HR, Hazard Ratios; CI, confidence interval; Adj: Adjusted; ap-value from Univariate Cox PH regression; bp-value from multivariable Cox PH regression; rreference level; *statistically significant (p<0.05)