TABLE 3.

Echocardiographic Outcomes Evaluating Structure and Function

	No History of HDP (n = 49)	History of HDP (n = 82)	P Value	Adjusted P Valuea
LV structure and function
Ejection fraction, %	56.4 ± 6.1	55.4 ± 5.2	0.36	0.44
IVS thickness, cm	0.89 ± 0.18	0.92 ± 0.18	0.27	0.82
PW thickness, cm	0.82 ± 0.15	0.84 ± 0.14	0.53	0.68
Relative wall thickness	0.36 ± 0.08	0.38 ± 0.09	0.34	0.71
LV mass	127.06 (108.79 to 141.91)	127.81 (108.46 to 153.27)	0.73	0.79
LV mass index	65.29 (55.52 to 74.72)	66.82 (56.43 to 79.94)	0.41	0.91
Diastolic function
E/A	1.34 (1.24 to 1.58)	1.34 (1.17 to 1.52)	0.73	0.36
Septal e’, cm/s	10 (9 to 12)	9 (8 to 11)	0.19	0.70
Lateral e’, cm/s	12 (10 to 14)	11.5 (9 to 14)	0.56	0.95
E’ average, cm/s	11 (9 to 13)	10.5 (8.5 to 12.5)	0.41	0.96
E/e’ average	7.23 (6.31 to 8.78)	8.26 (6.33 to 9.36)	0.19	0.78
Strain parameters
Longitudinal strain %	−20.6 (−22.5 to −18.9)	−20.3 (−22.2 to −18.5)	0.36	0.63
GLS < −18%	39 (85)	56 (77)	0.29	0.81
Circumferential strain	−22.8 (−25.8 to −20.6)	−24.6 (−28.5 to −21.9)	0.04	0.03
Ratio longitudinal/circumferential strain	0.91 (0.80 to 1.01)	0.83 (0.69 to 0.95)	0.01	0.09
Vascular and ventricular function
LV Ees	1.98 (1.59 to 2.31)	2.01 (1.76 to 2.37)	0.30	0.72
Ea	1.79 (1.46 to 1.98)	1.97 (1.57 to 2.24)	0.04	0.14
VA coupling (Ees/Ea)	1.15 ± 0.25	1.10 ± 0.24	0.25	0.59

Values are mean ± SD with 2-sided Student’s t-test P value, median (IQR) with Wilcoxon rank sum test P value, or n (%) with Fisher exact P value.

^aAdjusted for age, race, body mass index, history of preterm birth and presence of CHTN.

Ea = effective arterial elastance; Ees = end-systolic elastance; GLS = global longitudinal strain; HDP = hypertensive disorder of pregnancy; IVS = interventricular septum; LV = left ventricular; PW = posterior wall.