Skip to main content
. 2022 Aug 13;13(8):703. doi: 10.1038/s41419-022-05157-1

Fig. 7. CYTOR-HNRNPC-ZEB1 axis is a potential therapeutic target for treating OSCC.

Fig. 7

A HNRNPC and ZEB1 expression in specimens of OSCC patients. (n = 192) B Kaplan–Meier analysis of OS curves for OSCC patients with HNRNPC-low and HNRNPC-high expression. C OS curves for OSCC patients with ZEB1-low and ZEB1-high expression. D Correlations between CYTOR and HNRNPC, E HNRNPC and ZEB1, and F CYTOR and ZEB1 were determined by Spearman’s correlation assay. G Nude mice were injected with the luciferase-labeled oral cancer cells, si-CYTOR encapsuled NMOFs (UiO-66-NH2) were injected at day 21 post-injection of cancer cells. Lung-metastasized cells were measured at day 45 post-injection. H Representative images of H&E staining of lung-metastasized cancer cells. I Representative images of IHC staining of cytokine in lungs.