Metabolic pathways for the degradation of phthalate and the synthesis of nicotinic acid mononucleotide from quinolinate and phosphoribosyl pyrophosphate. A restriction map and diagram of the cloned and sequenced genes for phthalate degradation (including the nadC analogue ophE reported here) from B. cepacia DBO1 are shown at the bottom. A, AatII; B, BamHI; Bc, BclI; E, EcoRI; N, NotI; S, SalI; Sp, SphI. TCA, tricarboxylic acid.