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Summary of selected articles as evaluated in animal and human studies. A, Numbers of eligible studies published over time. B, Numbers of adjuvant(s) studied per study. Breakdown of adjuvants evaluated in human (C) and animal (D) studies. Abbreviations: B. pertussis, Bordetella pertussis; GLA-SE, glucopyranosyl lipid A in stable oil-in-water emulsion; ISCOM, immunostimulating complex; O/W, oil-in-water; PRR, pattern recognition receptor.
