TABLE 1.
Younger than 50 |
Older than 49 |
All |
|||||||
APOE4– | APOE4+ | p | APOE4– | APOE4+ | p | APOE4– | APOE4+ | p | |
N | 38 | 16 | 53 | 30 | 91 | 46 | |||
Age, years (SE) | 38.8 (1.3) | 39.5 (1.7) | 0.8 | 59.1 (0.9) | 59.8 (1.4) | 0.7 | 50.6 (1.3) | 52.7 (1.8) | 0.3 |
Sex m/w | 16/22 | 4/12 | 0.2 | 18/35 | 7/23 | 0.5 | 34/57 | 11/35 | 0.1 |
Education, years | 15.0 (0.2) | 15.0 (0.4) | 0.9 | 15.1 (0.1) | 15.0 (0.1) | 0.6 | 15.1 (0.1) | 15.0 (0.16) | 0.8 |
MMSE (SE) | 29.9 (0.14) | 30.0 (0.1) | 0.6 | 29.6 (0.2) | 29.5 (0.3) | 0.8 | 29.7 (0.1) | 29.6 (O.3) | 0.9 |
LMWT (SE) | 6.0 (0.2) | 5.9 (0.4) | 0.8 | 5.4 (0.2) | 5.2 (0.3) | 0.6 | 5.6 (0.2) | 5.4 (0.2) | 0.4 |
COWAT (SE) | 54.2 (2.5) | 52.7 (3.2) | 0.7 | 47.1 (1.6) | 47.1 (1.8) | 1.0 | 50.0 (1.4) | 48.9 (1.6) | 0.7 |
SST (SE) | 1.0 (0.2) | 0.8 (0.3) | 0.6 | 1.0 (0.15) | 0.6 (0.15) | 0.6 | 1.0 (0.1) | 0.6 (0.1) | 0.06 |
MMSE, mini-mental state examination; LMWT, Luria memory words test; COWAT, controlled oral word association test; SST, serial sevens subtraction test.