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GSDMD dominates organ damage, cellular and molecular regulation in sepsis. During sepsis, bacteria enter the blood, neutrophils increase the release of pro-inflammatory factors, reactive oxygen species and HMGB1, and the body produces coagulation dysfunction, lung injury, myocardial injury, liver injury, and intestinal injury. GSDMD, which functions as a motor, is usually involved in the damage of these molecules and the body
