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. 2022 Aug 1;14:955878. doi: 10.3389/fnagi.2022.955878

Table 2.

Meta-analysis of diet and supplements with risk of dementia.

Heterogeneity
Dementia/AD Diet and supplements vitamin E Studies ( n ) OR 95% CI P -value Model I2 (%) P -value
Vitamin E 15 0.79 0.70–0.88 0.012 Random 35.0 0.071
Dietary Vitamin E 8 0.78 0.65–0.95 0.004 Random 59.2 0.016
Vitamin E supplements 9 0.83 0.73–0.94 0.000 Random 30.6 0.173
Dementia Cohort study 14 0.79 0.69–0.89 0.000 Random 48.3 0.022
Case-control study 4 0.76 0.47–1.24 0.274 Random 0.0 0.799
>7 8 0.85 0.75–0.97 0.017 Random 0.0 0.445
< =7 10 0.76 0.65–0.89 0.000 Random 49.4 0.038
Vitamin E 9 0.78 0.64–0.94 0.001 Random 36.9 0.123
Dietary Vitamin E 5 0.83 0.64–1.09 0.182 Random 60.2 0.040
AD Vitamin E supplements 3 0.67 0.47–0.96 0.031 Random 0.0 0.460
Cohort study 8 0.77 0.63–0.94 0.010 Random 42.3 0.097
>7 3 0.63 0.36–1.15 0.136 Random 37.7 0.201
< =7 6 0.80 0.65–0.98 0.035 Random 44.1 0.111