Table 3.

Correlation coefficients of reproductive factors and MMSE score (Spearman’s rho).

Reproductive factors	C-MMSE scores
	All samples		MCI		Dementia
	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2
Age at menarche	−0.092***	0.023	−0.244***	0.048	−0.178***	0.017
Age at menopause	0.103***	0.070***	0.037	0.024	0.033	0.011
Reproductive period	0.129***	0.053**	0.150***	0.001	0.054	0.017
Number of pregnancies	−0.124***	−0.042**	−0.123***	−0.009	−0.401	0.002
Number of parities	−0.217***	−0.068***	−0.251***	0.002	−0.121*	−0.035
	AD		DLB		VaD
	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2
Age at menarche	−0.119	0.048	−0.627***	−0.486***	−0.109	−0.005
Age at menopause	0.038	0.034	−0.038	0.035	0.057	−0.076
Reproductive period	0.037	0.009	0.115	0.196	0.024	−0.064
Number of pregnancies	−0.027	−0.009	−0.159	−0.227	−0.046	−0.084
Number of parities	−0.061	−0.037	−0.224	−0.195	−0.267*	−0.192

Spearman’s correlation analysis was used to calculate the correlation between reproductive factors and C-MMSE scores in Model 1, and Model 2 was performed by adjusting age and education with partial correlation. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001.

C-MMSE, Mini-Mental State Examination (Chinese version); MCI, mild cognitive impairment; AD, Alzheimer’s disease; DLB, dementia with Lewy bodies; VaD, vascular dementia.