Table 2.
The characteristics of studies included in this meta-analysis (the correlation between vitamin D and the prognosis of depression).
| Author, year | Country | Follow-up (weeks) | Dose of experimental group | Sample size | Participants inclusion criteria | Depression assessment scale | |
|---|---|---|---|---|---|---|---|
| Experiment | Control | ||||||
| Yalamanchili and Gallagher (36) | USA | 144 | 200 IU/day (+HT) 200 IU/day |
122 123 |
120 123 |
Age: 65–77 years for postmenopausal women | GDS-30 |
| Khoraminya et al. (40) | Iran | 8 | 1,500 IU/day | 20 | 20 | Age: 18–65 years with MDD and deficiency of vitamin D | BDI-II, HAM-D |
| Mozaffari-Khosravi et al. (42) | Iran | 12 | 300,000 IU/3 months 150,000 IU/ 3 months |
39 36 |
34 | Age: 18–65 years with MDD, Free from other psychiatric diagnoses, any antidepressant drugs or dietary supplements | BDI-II |
| Wang et al. (44) | China | 52 | 50,000 IU/week | 362 | 364 | Age: 20 to 60 years for dialysis patients with MDD and deficiency of vitamin D, Free from other psychiatric diagnoses,any antidepressant drugs or dietary supplements | BDI-II |
| Sepehrmanesh et al. (43) | Iran | 8 | 50,000 IU/week | 18 | 18 | Age: 18–65 years with MDD | BDI-II |
| Hansen et al. (39) | Denmark | 24 | 2,800 IU/day | 28 | 34 | Age: 50–79 years with MDD | HAM-D17, MDI |
| Alavi et al. (37) | Iran | 8 | 50,000 IU/week | 39 | 39 | Age > 60 years with MDD and deficiency of vitamin D, Free from other psychiatric diagnoses | GDS-15 |
| Zhang et al. (45) | China | 8 | 100,000 IU/week | 58 | 65 | Age ≥ 18 years for recurrent pulmonary tuberculosis patients with MDD | BDI-II |
| Amini et al. (38) | Iran | 8 | 50,000 IU/fortnight 50,000 IU/fortnight(+Ca) |
26 26 |
24 | BMI ≤ 35 kg/m2 for women with PPD | EPDS |
| Libuda et al. (41) | Germany | 4 | 2,640 IU/day | 56 | 57 | Patients with MDD and low 25(OH)D levels | BDI-II, DISYPS-II |
| Abiri et al. (7) | Iran | 8 | 50,000 IU/week (+Mg) 50,000 IU/week |
25 26 |
26 25 |
BMI: 35 kg/m2, Age > 20 years for women with MDD and low 25(OH)D levels | BDI-II |
MDD, Major depressive disorder; PPD, Postpartum depression; BMI, body mass index; NA, no available; BDI, Beck Depression Inventory; HAM-D, Hamilton Depression Rating Scale; MDI, Major depression inventory; GDS, Geriatric Depression Scale; EPDS, Edinburgh Postnatal Depression Scale; DISYPS-II, Diagnostic System for Mental Disorders in Children and Adolescents according to ICD-10 and DSM-IV.