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. 2022 Aug 1;10:903547. doi: 10.3389/fpubh.2022.903547

Table 3.

Subgroup analysis of the correlation between vitamin D and the incidence/prognosis of depression.

Subgroup No. of studies Participants Changes in depression SMD 95%CI p Heterogeneity(I2) (%)
Occurrence
BDI 9 1,305 −0.36 −0.65–(−0.07) 0.02 83
Overweight (BMI >24 kg/m2) 4 497 - −0.11 −0.29–0.06 0.21 0
Nomal weight (BMI: 18–24kg/m2) 13 3,721 −0.28 −0.49–(−0.07) 0.01 83
The elderly (≥50 years old) 2 2,432 - 0.04 −0.04–0.12 0.29 0
Female 7 2,922 −0.44 −0.81–(−0.06) 0.02 91
Older female 2 2,432 - 0.04 −0.04–0.12 0.29 0
Intervention duration ≤ 8 weeks 3 251 - −0.55 −1.61–0.52 0.32 93
≥8 weeks 16 4,054 −0.15 −0.28–(−0.01) 0.03 60
Development
BDI 7 1,236 - −1.04 −2.29–0.21 0.10 99
Overweight (BMI >24 kg/m2) 2 178 −0.79 −1.34–(−0.24) 0.005 72
Nomal weight (BMI: 18–24 kg/m2) 4 445 −0.34 −0.68–0.00 0.05 60
Female 3 448 −0.61 −1.16–(−0.06) 0.03 84
Intervention duration ≤ 8 weeks 7 555 −0.69 −1.08–(−0.30) <0.001 80
≥8 weeks 10 1,656 −1.00 −1.90–(−0.09) 0.03 98

SMD, standard mean difference; BMI, body mass index; BDI, Beck Depression Inventory.

-, There was no statistical difference in the change of depression scores between the experimental and control groups.

↓, The depression scores of the experimental group decreased compared with control groups.