Table 1.

Diagnostic criteria for metabolic syndrome (MetS)

	WHO19	NCEP ATP III16	IDF18	AHA/NHLBI17
Required criteria	Dysglycemia and at least two other factors	Three or more of the following	Central obesity and at least two other factors	Three or more of the following
CO	W/H > 0.90 (M) or W/H > 0.85 (F) and/or BMI > 30 kg/m2	WC > 40 inches (M) or WC > 35 inches (F)	Defined by WC*	WC ≥ 40 inches (M) or WC ≥ 35 inches (F)
TG	TG ≥ 150 mg/dL and/or HDLc < 35 mg/dL (M) or <39 mg/dL (F)†	≥150 mg/dL	≥150 mg/dL or drug treatment for elevated TG	≥150 mg/dL or drug treatment for elevated TG
HDLc		<40 mg/dL (M) or <50 mg/dL (F)	<40 mg/dL (M) or <50 mg/dL (F) or drug treatment for reduced HDLc	<40 mg/dL (M) or <50 mg/dL (F) or drug treatment for reduced HDLc
HTN	≥140/90 mmHg	≥130/85 mmHg	SBP ≥ 130 mm Hg or DBP ≥ 85 mmHg or antihypertensive drug treatment	SBP ≥ 130 mmHg or DBP ≥ 85 mmHg or antihypertensive drug treatment
Dysglycemia	Glucose intolerance, IGT or T2DM and/or IR	Fasting glucose ≥110 mg/dL	FPG ≥ 100 mg/dL or previous diagnosis of T2DM	Fasting glucose ≥ 100 mg/dL or drug treatment for hyperglycemia
Other	Microalbuminuria‡

AHA/NHLBI, American Heart Association and National Heart, Lung, and Blood Institute; BMI, body mass index; CO, central obesity; DBP, diastolic blood pressure; F, female; FPG, fasting plasma glucose; HDLc, high-density-lipoprotein cholesterol; HTN, hypertension; IDF, International Diabetes Federation; IGT, impaired glucose tolerance; IR, insulin resistance; M, male; NCEP ATP III, National Cholesterol Education Program's Adult Treatment Panel III; SBP, systolic blood pressure; T2DM, type 2 diabetes mellitus; TG, triglycerides; WC, waist circumference; W/H, waist-to-hip ratio; WHO, World Health Organization.

^*Variable according to sex and ethnic group.

^†Hypertriglyceridemia and reduced HDLc fulfil the same criteria.

^‡Defined as urinary albumin excretion rate ≥20 μg/min, or albumin:creatinine ratio ≥30 mg/g.