Table 3.
Top disease functions for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis identified by Ingenuity Pathway Analysis
|
Top disease functions in NAFLD vs healthy control
|
P
values
|
| Inflammatory response | 1.67E-03 |
| Liver lesion | 6.59E-05 |
| Cell movement of epithelial cells | 3.88E-04 |
| Activation of cells | 5.30E-04 |
| Synthesis of lipid | 5.49E-08 |
| Accumulation of lipid | 6.12E-04 |
| Concentration of lipid | 2.38E-06 |
| Fibrosis | 3.75E-05 |
| Secretion of lipid | 1.06E-03 |
| Hepatic injury | 1.54E-04 |
| Organismal injury and abnormalities | 5.10E-16 |
| Cancer | 3.47E-15 |
| Dermatologic diseases and conditions | 5.20E-11 |
| Metabolic disease | 6.69E-10 |
| Lipid metabolism | 8.09E-12 |
| Molecular transport | 7.06E-12 |
| Small molecule biochemistry | 9.86E-11 |
| Cell death and survival | 5.05E-8 |
| Cellular movement | 6.28E-8 |
| Adipogenesis | 1.31E-7 |
NAFLD: Non-alcoholic fatty liver disease.