Table 4.

Top five molecular networks associated with genetic differences in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis liver biopsies compared to healthy controls. Disease networks were identified using Ingenuity Pathway Analysis

Top molecular networks in NAFLD vs healthy control
Lipid metabolism, small molecule biochemistry, vitamin and mineral metabolism	34
Cell-to-cell signaling and interaction, cellular movement, hematological system development and function	23
Connective tissue disorders, inflammatory disease, organismal injury and abnormalities	19
Cellular development, connective tissue development and function, skeletal and muscular system development and function	16
Cell death and survival, neurological disease, organismal injury and abnormalities	16
Amino acid metabolism, molecular transport, small molecule biochemistry	34
Cellular development, skeletal and muscular system development and function, tissue development	34
Hereditary disorder, neurological disease, organismal injury and abnormalities	32
Digestive system development and function, lipid metabolism, small molecule biochemistry	29
Cell cycle, cell death and survival, cellular movement	29

NAFLD: Non-alcoholic fatty liver disease.