Table 1.

Demographic and clinical features of RA patients and controls.

Characteristic	RA patients				Healthy Controls
Age: range years	22 – 83				31 – 74
Sex: female/male	53/10				15/3
Treatment:	untreated	MTX	anti-TNF	TOFA
CRP: median ± QD, mg/l	12 ± 9.2	6.0 ± 2.8	5.0 ± 3.2	6.0 ± 4.5
ESR: median ± QD, mm/h	19 ± 15	11 ± 7	9 ± 9	21 ± 7
DAS28 ESR: mean ± SEM	4.9 ± 0.3	3.4 ± 0.3	3.9 ± 0.3	3.4 ± 0.4
Anti-CCP: positive/negative	15/5	13/5	10/5	7/3
RF: positive/negative	15/5	11/7	10/5	7/3

RA, Rheumatoid arthritis; MTX, methotrexate; TOFA, JAK inhibitor Tofacitinib; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; DAS28, disease activity score 28; Anti-CCP, Anti-cyclic citrullinated peptide antibodies; RF, rheumatoid factor.