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. Author manuscript; available in PMC: 2022 Aug 15.
Published in final edited form as: Pharmacology. 2022 May 12;107(7-8):406–416. doi: 10.1159/000524386

Fig. 3. Fenretinide prevents alcohol suppression of gut canonical Notch signaling.

Fig. 3.

Quantitative PCR (qPCR) histograms of A-D) ileal, and G-J) colonic relative mRNA levels of genes involved in canonical Notch signaling, Notch1, Notch2, Hes1 and Hey1. E) and K) Representative images, and F) and L) quantification of ileal, and colonic Notch intra-cellular domain (NICD) immunohistochemistry (IHC) (yellow arrows). Magnification: ×200; scale bar = 100 μm. All histogram errors bars represent ±SD, with *p< 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns = not significant. qPCR results represent gene fold changes relative to pair-fed mice normalized against the housekeeping gene 36B4.