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. 2022 Aug 1;13(8):1351–1357. doi: 10.1021/acsmedchemlett.2c00280

Table 2. Investigation of the S3 Site Binding Moiety.

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a

IC50 values are shown as the mean of duplicate measurements and calculated from the concentration–inhibition curve using Origin software (version 5.0, Microcal Software, Inc.).

b

IC50 values are shown as the mean of duplicate measurements and calculated from the concentration–inhibition curve using SAS software (version 9.1.3, SAS Institute Inc.).

c

Rahuel, J., et al. reported the IC50 values against rh-renin and hPRA were both 0.6 nM.9